Human M1 macrophages express unique innate immune response genes after mycobacterial infection to defend against tuberculosis

Mycobacterium tuberculosis (Mtb) is responsible for approximately 1.5 million deaths each year. Though 10% of patients develop tuberculosis (TB) after infection, 90% of these infections are latent. Further, mice are nearly uniformly susceptible to Mtb but their M1-polarized macrophages (M1-MΦs) can...

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Detalles Bibliográficos
Autores principales: Khan, Arshad, Zhang, Kangling, Singh, Vipul K., Mishra, Abhishek, Kachroo, Priyanka, Bing, Tian, Won, Jong Hak, Mani, Arunmani, Papanna, Ramesha, Mann, Lovepreet K., Ledezma-Campos, Eder, Aguillon-Duran, Genesis, Canaday, David H., David, Sunil A., Restrepo, Blanca I., Viet, Nhung Nguyen, Phan, Ha, Graviss, Edward A., Musser, James M., Kaushal, Deepak, Gauduin, Marie Claire, Jagannath, Chinnaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119986/
https://www.ncbi.nlm.nih.gov/pubmed/35590096
http://dx.doi.org/10.1038/s42003-022-03387-9

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