PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression

Although stromal fibroblasts play a critical role in cancer progression, their identities remain unclear as they exhibit high heterogeneity and plasticity. Here, a master transcription factor (mTF) constructing core-regulatory circuitry, PRRX1, which determines the fibroblast lineage with a myofibro...

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Detalles Bibliográficos
Autores principales: Lee, Keun-Woo, Yeo, So-Young, Gong, Jeong-Ryeol, Koo, Ok-Jae, Sohn, Insuk, Lee, Woo Yong, Kim, Hee Cheol, Yun, Seong Hyeon, Cho, Yong Beom, Choi, Mi-Ae, An, Sugyun, Kim, Juhee, Sung, Chang Ohk, Cho, Kwang-Hyun, Kim, Seok-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120014/
https://www.ncbi.nlm.nih.gov/pubmed/35589735
http://dx.doi.org/10.1038/s41467-022-30484-4

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