NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes

The transcription factor nuclear factor-κB (NF-κB) has a key role in the pathogenesis of diabetes and its complications. Although activation of the canonical NF-κB pathway in β-cells is generally deleterious, little is known about the role of the non-canonical NF-κB signalling and its main regulator...

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Detalles Bibliográficos
Autores principales: Xiao, Peng, Takiishi, Tatiana, Violato, Natalia Moretti, Licata, Giada, Dotta, Francesco, Sebastiani, Guido, Marselli, Lorella, Singh, Sumeet Pal, Sze, Mozes, Van Loo, Geert, Dejardin, Emmanuel, Gurzov, Esteban Nicolas, Cardozo, Alessandra Kupper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120028/
https://www.ncbi.nlm.nih.gov/pubmed/35589698
http://dx.doi.org/10.1038/s41419-022-04931-5

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