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Tumor suppressor p53 restrains cancer cell dissemination by modulating mitochondrial dynamics

Tumor suppressor p53 plays a central role in preventing tumorigenesis. Here, we unravel how p53 modulates mitochondrial dynamics to restrain the metastatic properties of cancer cells. p53 inhibits the mammalian target of rapamycin complex 1 (mTORC1) signaling to attenuate the protein level of mitoch...

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Detalles Bibliográficos
Autores principales:	Phan, Trinh T. T., Lin, Yu-Chun, Chou, Yu-Ting, Wu, Chien-Wei, Lin, Lih-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120037/ https://www.ncbi.nlm.nih.gov/pubmed/35589683 http://dx.doi.org/10.1038/s41389-022-00401-x

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