Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces

Cholesterol is a major regulator of multiple types of ion channels. Although there is increasing information about cholesterol binding sites, the molecular mechanisms through which cholesterol binding alters channel function are virtually unknown. In this study, we used a combination of Martini coar...

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Detalles Bibliográficos
Autores principales: Barbera, Nicolas, Granados, Sara T., Vanoye, Carlos Guillermo, Abramova, Tatiana V., Kulbak, Danielle, Ahn, Sang Joon, George, Alfred L., Akpa, Belinda S., Levitan, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120057/
https://www.ncbi.nlm.nih.gov/pubmed/35602957
http://dx.doi.org/10.1016/j.isci.2022.104329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120057/
https://www.ncbi.nlm.nih.gov/pubmed/35602957
http://dx.doi.org/10.1016/j.isci.2022.104329

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