TGF-β1/SH2B3 axis regulates anoikis resistance and EMT of lung cancer cells by modulating JAK2/STAT3 and SHP2/Grb2 signaling pathways

The pathogenesis of lung cancer, the most common cancer, is complex and unclear, leading to limited treatment options and poor prognosis. To provide molecular insights into lung cancer development, we investigated the function and underlying mechanism of SH2B3 in the regulation of lung cancer. We in...

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Detalles Bibliográficos
Autores principales: Wang, Li-Na, Zhang, Zi-Teng, Wang, Li, Wei, Hai-Xiang, Zhang, Tao, Zhang, Li-Ming, Lin, Hang, Zhang, Heng, Wang, Shao-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120066/
https://www.ncbi.nlm.nih.gov/pubmed/35589677
http://dx.doi.org/10.1038/s41419-022-04890-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120066/
https://www.ncbi.nlm.nih.gov/pubmed/35589677
http://dx.doi.org/10.1038/s41419-022-04890-x

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