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Role of Platelet-activating factor and HO-1 in mediating the protective effect of rupatadine against 5-fluorouracil-induced hepatotoxicity in rats

5-fluorouracil (5-FU) is a widely used chemotherapeutic drug, but its hepatotoxicity challenges its clinical use. Thus, searching for a hepatoprotective agent is highly required to prevent the accompanied hepatic hazards. The current study aimed to investigate the potential benefit and mechanisms of...

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Detalles Bibliográficos
Autores principales:	Khalaf, Hanaa Mohamed, Hafez, Sara Mohamed Naguib Abdel, Abdalla, Ahlam Mohamed, Welson, Nermeen N., Abdelzaher, Walaa Yehia, Abdelbaky, Fatma Alzhraa Fouad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120097/ https://www.ncbi.nlm.nih.gov/pubmed/35119631 http://dx.doi.org/10.1007/s11356-022-18899-4

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