Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

Neuronal activity is emerging as a driver of central and peripheral nervous system cancers. Here, we examined neuronal physiology in mouse models of the tumor predisposition syndrome Neurofibromatosis-1 (NF1), with different propensities to develop nervous system cancers. We show that central and pe...

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Detalles Bibliográficos
Autores principales: Anastasaki, Corina, Mo, Juan, Chen, Ji-Kang, Chatterjee, Jit, Pan, Yuan, Scheaffer, Suzanne M., Cobb, Olivia, Monje, Michelle, Le, Lu Q., Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120229/
https://www.ncbi.nlm.nih.gov/pubmed/35589737
http://dx.doi.org/10.1038/s41467-022-30466-6

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