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Effect of excess weight and insulin resistance on DNA methylation in prepubertal children

Epigenetic mechanisms, such as DNA methylation, regulate gene expression and play a role in the development of insulin resistance. This study evaluates how the BMI z-score (BMIz) and the homeostatic model assessment of insulin resistance (HOMA-IR), alone or in combination, relate to clinical outcome...

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Detalles Bibliográficos
Autores principales:	Barbosa, Pedro, Landes, Reid D., Graw, Stefan, Byrum, Stephanie D., Bennuri, Sirish, Delhey, Leanna, Randolph, Chris, MacLeod, Stewart, Reis, Andreia, Børsheim, Elisabet, Rose, Shannon, Carvalho, Eugenia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120504/ https://www.ncbi.nlm.nih.gov/pubmed/35589784 http://dx.doi.org/10.1038/s41598-022-12325-y

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