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Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models

BACKGROUND: Sorafenib is effective in treating hepatoma, but most patients develop resistance to it. STAT3 signaling has been implicated in sorafenib resistance. Artesunate (ART) and 20(R)-ginsenoside Rg3 (Rg3) have anti-hepatoma effects and can inhibit STAT3 signaling in cancer cells. This study ai...

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Detalles Bibliográficos
Autores principales:	Chen, Ying-Jie, Wu, Jia-Ying, Deng, Yu-Yi, Wu, Ying, Wang, Xiao-Qi, Li, Amy Sze-man, Wong, Lut Yi, Fu, Xiu-Qiong, Yu, Zhi-Ling, Liang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120623/ https://www.ncbi.nlm.nih.gov/pubmed/35600776 http://dx.doi.org/10.1016/j.jgr.2021.07.002

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