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Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression

BACKGROUND: Brain-derived neurotrophic factor (BDNF)–tropomyosin-related kinase B (TrkB) plays a critical role in the pathogenesis of depression by modulating synaptic structural remodeling and functional transmission. Previously, we have demonstrated that the ginsenoside Rb1 (Rb1) presents a novel...

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Detalles Bibliográficos
Autores principales:	Wang, Guoli, An, Tianyue, Lei, Cong, Zhu, Xiaofeng, Yang, Li, Zhang, Lianxue, Zhang, Ronghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120625/ https://www.ncbi.nlm.nih.gov/pubmed/35600767 http://dx.doi.org/10.1016/j.jgr.2021.03.005

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