Structural determinants of acid-sensing ion channel potentiation by single chain lipids

Acid-sensing ion channels (ASICs) are sensitized to activation by inflammatory mediators such as the polyunsaturated fatty acid (PUFA) arachidonic acid (AA). Previous work has shown that AA can potentiate ASIC currents at subsaturating proton concentrations, but the structural mechanisms of this cha...

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Detalles Bibliográficos
Autores principales: Klipp, Robert C., Bankston, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120901/
https://www.ncbi.nlm.nih.gov/pubmed/35583813
http://dx.doi.org/10.1085/jgp.202213156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120901/
https://www.ncbi.nlm.nih.gov/pubmed/35583813
http://dx.doi.org/10.1085/jgp.202213156

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