Design, Synthesis, and Preliminary Evaluation of [(68)Ga]Ga-NOTA-Insulin as a PET Probe in an Alzheimer’s Disease Mouse Model

[Image: see text] Aberrant insulin signaling has been considered one of the risk factors for the development of Alzheimer’s disease (AD) and has drawn considerable attention from the research community to further study its role in AD pathophysiology. Herein, we describe the development of an insulin...

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Detalles Bibliográficos
Autores principales: Taubel, Jillissa C., Nelson, Nicholas R., Bansal, Aditya, Curran, Geoffrey L., Wang, Lushan, Wang, Zengtao, Berg, Heather M., Vernon, Cynthia J., Min, Hoon-Ki, Larson, Nicholas B., DeGrado, Timothy R., Kandimalla, Karunya K., Lowe, Val J., Pandey, Mukesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121347/
https://www.ncbi.nlm.nih.gov/pubmed/35420782
http://dx.doi.org/10.1021/acs.bioconjchem.2c00126

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