Cargando…

Design of an Organocatalytic Asymmetric (4 + 3) Cycloaddition of 2-Indolylalcohols with Dienolsilanes

[Image: see text] Here we present the design of a highly enantioselective, catalytic (4 + 3) cycloaddition of gem-dialkyl 2-indolyl alcohols and dienolsilanes, enabled by strong and confined IDPi Lewis acids. The method furnishes novel bicyclo[3.2.2]cyclohepta[b]indoles with up to three stereogenic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ouyang, Jie, Maji, Rajat, Leutzsch, Markus, Mitschke, Benjamin, List, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121375/ https://www.ncbi.nlm.nih.gov/pubmed/35523203 http://dx.doi.org/10.1021/jacs.2c02216

Ejemplares similares

Asymmetric Catalytic Friedel–Crafts Reactions of Unactivated Arenes
por: Brunen, Sebastian, et al.
Publicado: (2023)

A Catalytic Asymmetric Hydrolactonization
por: Maji, Rajat, et al.
Publicado: (2023)

Organocatalytic Asymmetric [2 + 4] Cycloadditions of 3-Vinylindoles with ortho-Quinone Methides
por: Liu, Si-Jia, et al.
Publicado: (2021)

Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
por: Amatov, Tynchtyk, et al.
Publicado: (2021)

Asymmetric Synthesis of Axially Chiral Molecules via Organocatalytic Cycloaddition and Cyclization Reactions
por: Cai, Wei-Yun, et al.
Publicado: (2023)

Organocatalytic stereoselective cyanosilylation of small ketones
por: Zhou, Hui, et al.
Publicado: (2022)

Organocatalytic DYKAT of Si-Stereogenic Silanes
por: Zhou, Hui, et al.
Publicado: (2023)

Asymmetric synthesis of chiral 1,2-oxazinane and hexahydropyridazin spirocyclic scaffolds by organocatalytic [4 + 2] cycloaddition
por: Tian, Heng-Zhi, et al.
Publicado: (2022)

Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers
por: Zhou, Hui, et al.
Publicado: (2022)

Organocatalytic cycloaddition–elimination cascade for atroposelective construction of heterobiaryls
por: Xu, Wen-Lei, et al.
Publicado: (2021)

The Catalytic Asymmetric Intermolecular Prins Reaction
por: Díaz-Oviedo, C. David, et al.
Publicado: (2021)

Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls
por: Yang, Hui, et al.
Publicado: (2022)

Catalytic Asymmetric Synthesis of Unprotected β(2)-Amino Acids
por: Zhu, Chendan, et al.
Publicado: (2021)

Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds: Focus Review
por: Kennemur, Jennifer L., et al.
Publicado: (2021)

Organocatalytic asymmetric chlorinative dearomatization of naphthols
por: Yin, Qin, et al.
Publicado: (2015)

Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, Aliphatic N‐Acyliminium Ions
por: Grossmann, Oleg, et al.
Publicado: (2022)

Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones
por: Žari, Sergei, et al.
Publicado: (2012)

Catalytic asymmetric synthesis of cannabinoids and menthol from neral
por: Grimm, Joyce A. A., et al.
Publicado: (2023)

Catalytic Asymmetric Spirocyclizing Diels–Alder Reactions of Enones: Stereoselective Total and Formal Syntheses of α-Chamigrene, β-Chamigrene, Laurencenone C, Colletoic Acid, and Omphalic Acid
por: Ghosh, Santanu, et al.
Publicado: (2022)

Organocatalytic asymmetric synthesis of P-stereogenic molecules
por: Liu, Junyang, et al.
Publicado: (2023)

Direct and Catalytic C‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside
por: Obradors, Carla, et al.
Publicado: (2022)

Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone
por: Yu, Jin-Sheng, et al.
Publicado: (2012)

Dataset of asymmetric intramolecular [4+3] cycloaddition reactions catalyzed by NHC-gold(I) complexes
por: Ma, Ruoyu, et al.
Publicado: (2019)

Towards an asymmetric organocatalytic α-cyanation of β-ketoesters
por: Chowdhury, Raghunath, et al.
Publicado: (2015)

Towards an Asymmetric Organocatalytic α-Azidation of β-Ketoesters
por: Tiffner, Maximilian, et al.
Publicado: (2018)

Organocatalytic chiral polymeric nanoparticles for asymmetric aldol reaction
por: Abuaf, Meir, et al.
Publicado: (2023)

Asymmetric counteranion-directed Lewis acid organocatalysis for the scalable cyanosilylation of aldehydes
por: Zhang, Zhipeng, et al.
Publicado: (2016)

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives
por: Auria-Luna, Fernando, et al.
Publicado: (2018)

Organocatalytic asymmetric fluorination of α-chloroaldehydes involving kinetic resolution
por: Shibatomi, Kazutaka, et al.
Publicado: (2014)

Absolute and relative facial selectivities in organocatalytic asymmetric chlorocyclization reactions
por: Salehi Marzijarani, Nastaran, et al.
Publicado: (2018)

Organocatalytic asymmetric nitroso aldol reaction of α-substituted malonamates
por: Gupta, Ekta, et al.
Publicado: (2022)

Strong and Confined Acids Control Five Stereogenic Centers in Catalytic Asymmetric Diels–Alder Reactions of Cyclohexadienones with Cyclopentadiene
por: Ghosh, Santanu, et al.
Publicado: (2020)

Organocatalytic Asymmetric Approach to γ,δ-Functionalization of 3-Cyano-4-styrylcoumarins via Bifunctional Catalysis
por: Romaniszyn, Marta, et al.
Publicado: (2022)

Organocatalytic asymmetric selenofunctionalization of tryptamine for the synthesis of hexahydropyrrolo[2,3-b]indole derivatives
por: Wei, Qiang, et al.
Publicado: (2013)

Organocatalytic Asymmetric Aldol Reaction of Arylglyoxals and Hydroxyacetone: Enantioselective Synthesis of 2,3-Dihydroxy-1,4-diones
por: Zhou, Yu-Hao, et al.
Publicado: (2020)

Organocatalytic asymmetric Michael/acyl transfer reaction between α-nitroketones and 4-arylidenepyrrolidine-2,3-diones
por: Parida, Chandrakanta, et al.
Publicado: (2021)

Asymmetric total synthesis of smyrindiol employing an organocatalytic aldol key step
por: Enders, Dieter, et al.
Publicado: (2012)

Organocatalytic asymmetric allylic amination of Morita–Baylis–Hillman carbonates of isatins
por: Zhang, Hang, et al.
Publicado: (2012)

Recent advances in organocatalytic asymmetric aza-Michael reactions of amines and amides
por: Sharma, Pratibha, et al.
Publicado: (2021)

Organocatalytic asymmetric synthesis of α-amino esters from sulfoxonium ylides
por: Guo, Wengang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6jhq35peg9fl1hpqd412bpigcq