Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants

BACKGROUND: Genome-wide association studies (GWASs) have identified multiple risk loci for bipolar disorder (BD). However, pinpointing functional (or causal) variants in the reported risk loci and elucidating their regulatory mechanisms remain challenging. METHODS: We first integrated chromatin immu...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Yang, Zhihui, Liu, Jiewei, Cai, Xin, Huo, Yongxia, Zhang, Zhijun, Li, Ming, Chang, Hong, Luo, Xiong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121601/
https://www.ncbi.nlm.nih.gov/pubmed/35590387
http://dx.doi.org/10.1186/s13073-022-01057-3

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