Effectiveness and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps and associated comorbidities: a multicentric prospective study in real life

BACKGROUND: Biologics are currently one of the main treatment options for a number of diseases. The IgG4 monoclonal antibody dupilumab targets the Interleukin-4 receptor alpha chain, thus preventing the biological effects of the cytokines IL-4 and IL-13, that are essential for the Th2 response. Seve...

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Detalles Bibliográficos
Autores principales: Nettis, Eustachio, Brussino, Luisa, Patella, Vincenzo, Bonzano, Laura, Detoraki, Aikaterini, Di Leo, Elisabetta, Sirufo, Maria Maddalena, Caruso, Cristiano, Lodi Rizzini, Fabio, Conte, Mariaelisabetta, Yacoub, Mona-Rita, Triggiani, Massimo, Ridolo, Erminia, Macchia, Luigi, Rolla, Giovanni, Brancaccio, Raffaele, De Paulis, Amato, Spadaro, Giuseppe, Di Bona, Danilo, D’Uggento, Angela Maria, Ginaldi, Lia, Gaeta, Francesco, Nucera, Eleonora, Jaubashi, Kliljeda, Villalta, Danilo, Dagna, Lorenzo, Ciotta, Domenico, Pucciarini, Francesco, Bagnasco, Diego, Celi, Giorgio, Chieco Bianchi, Fulvia, Cosmi, Lorenzo, Costantino, Maria Teresa, Crivellaro, Maria Angiola, D’Alò, Simona, del Biondo, Pietro, Del Giacco, Stefano, Di Gioacchino, Mario, Di Pietro, Linda, Favero, Elisabetta, Gangemi, Sebastiano, Guarnieri, Gabriella, Heffler, Enrico, Leto Barone, Maria Stefania, Lombardo, Carla, Losa, Francesca, Matucci, Andrea, Minciullo, Paola Lucia, Parronchi, Paola, Passalacqua, Giovanni, Pucci, Stefano, Rossi, Oliviero, Salvati, Lorenzo, Schiappoli, Michele, Senna, Gianenrico, Vianello, Andrea, Vultaggio, Alessandra, Baoran, Yang, Incorvaia, Cristoforo, Canonica, Giorgio Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121619/
https://www.ncbi.nlm.nih.gov/pubmed/35590407
http://dx.doi.org/10.1186/s12948-022-00171-2

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