Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence

Glomerular diseases are one of the most challenging entities in terms of diagnosis and management, especially when associated with systemic illnesses such as malignant disorders. Herein, a case of crescentic glomerulonephritis (CrGN) associated with polycythaemia vera (PV) in a 50-year-old female is...

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Autores principales: Dwivedi, Rohan, Shashikiran, K. B., Manuel, Sonu, Ansari, Faizan A., Raju, Sree B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121729/
https://www.ncbi.nlm.nih.gov/pubmed/35603102
http://dx.doi.org/10.4103/ijn.IJN_21_20
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author Dwivedi, Rohan
Shashikiran, K. B.
Manuel, Sonu
Ansari, Faizan A.
Raju, Sree B.
author_facet Dwivedi, Rohan
Shashikiran, K. B.
Manuel, Sonu
Ansari, Faizan A.
Raju, Sree B.
author_sort Dwivedi, Rohan
collection PubMed
description Glomerular diseases are one of the most challenging entities in terms of diagnosis and management, especially when associated with systemic illnesses such as malignant disorders. Herein, a case of crescentic glomerulonephritis (CrGN) associated with polycythaemia vera (PV) in a 50-year-old female is described. She presented with bilateral pedal oedema, splenomegaly, renal dysfunction and severe proteinuria. On evaluation, we found PV and CrGN. Renal involvement in PV is rare and generally considered as a manifestation of hypervolemia or high-viscosity-induced renal hyper-perfusion and hyper-filtration. This is a unique case of immunologically-mediated renal disease in PV.
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spelling pubmed-91217292022-05-21 Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence Dwivedi, Rohan Shashikiran, K. B. Manuel, Sonu Ansari, Faizan A. Raju, Sree B. Indian J Nephrol Case Report Glomerular diseases are one of the most challenging entities in terms of diagnosis and management, especially when associated with systemic illnesses such as malignant disorders. Herein, a case of crescentic glomerulonephritis (CrGN) associated with polycythaemia vera (PV) in a 50-year-old female is described. She presented with bilateral pedal oedema, splenomegaly, renal dysfunction and severe proteinuria. On evaluation, we found PV and CrGN. Renal involvement in PV is rare and generally considered as a manifestation of hypervolemia or high-viscosity-induced renal hyper-perfusion and hyper-filtration. This is a unique case of immunologically-mediated renal disease in PV. Wolters Kluwer - Medknow 2022 2022-03-09 /pmc/articles/PMC9121729/ /pubmed/35603102 http://dx.doi.org/10.4103/ijn.IJN_21_20 Text en Copyright: © 2022 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Dwivedi, Rohan
Shashikiran, K. B.
Manuel, Sonu
Ansari, Faizan A.
Raju, Sree B.
Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title_full Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title_fullStr Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title_full_unstemmed Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title_short Crescentic Glomerulonephritis Associated with Polycythaemia Vera: A Rare Occurrence
title_sort crescentic glomerulonephritis associated with polycythaemia vera: a rare occurrence
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121729/
https://www.ncbi.nlm.nih.gov/pubmed/35603102
http://dx.doi.org/10.4103/ijn.IJN_21_20
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