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Novel Oxime-Derivatized Synthetic Triterpene Glycosides as Potent Saponin Vaccine Adjuvants
Vaccine adjuvants are key for optimal vaccine efficacy, increasing the immunogenicity of the antigen and potentiating the immune response. Saponin adjuvants such as the carbohydrate-based QS-21 natural product are among the most promising candidates in vaccine formulations, but suffer from inherent...
Autores principales: | Fuentes, Roberto, Aguinagalde, Leire, Pifferi, Carlo, Plata, Adrián, Sacristán, Nagore, Castellana, Donatello, Anguita, Juan, Fernández-Tejada, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121768/ https://www.ncbi.nlm.nih.gov/pubmed/35603193 http://dx.doi.org/10.3389/fimmu.2022.865507 |
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