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Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study
Introduction: Ischemic colitis (IC) results from compromised blood flow to the colon. Risk factors include atrial fibrillation (A.Fib), peripheral artery disease (PAD), coronary artery disease (CAD), and congestive heart failure (CHF). However, few studies compared the mortality rate and colectomy b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121910/ https://www.ncbi.nlm.nih.gov/pubmed/35602840 http://dx.doi.org/10.7759/cureus.24308 |
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author | Mahfouz, Ratib Kozai, Landon A Obeidat, Adham E Darweesh, Mohammad Mansour, Mahmoud M Douglas, Mustafa F Berthiaume, Eric |
author_facet | Mahfouz, Ratib Kozai, Landon A Obeidat, Adham E Darweesh, Mohammad Mansour, Mahmoud M Douglas, Mustafa F Berthiaume, Eric |
author_sort | Mahfouz, Ratib |
collection | PubMed |
description | Introduction: Ischemic colitis (IC) results from compromised blood flow to the colon. Risk factors include atrial fibrillation (A.Fib), peripheral artery disease (PAD), coronary artery disease (CAD), and congestive heart failure (CHF). However, few studies compared the mortality rate and colectomy between patients with IC with CHF and IC alone. Objective: We aim to investigate the possibility of worse outcomes in patients with IC and CHF compared to IC alone. Methodology: Using the National Inpatient Sample database from 2016 to 2019, we obtained baseline demographic data, total hospital charge, rate of colectomy, length of hospital stay (LOS), and in-hospital mortality. Data were compared using a t-test and chi-squared. Odds ratios for comorbidities including A.Fib, CAD, PAD, end-stage renal disease, chronic obstructive pulmonary disease, hyperlipidemia, hypertension, diabetes, and cirrhosis were calculated. Results: 106,705 patients with IC were identified, among which 15,220 patients also had CHF. IC patients with CHF had a longer LOS (6.6 days vs 4.4 days; P<0.0001), higher total hospital charge ($71,359 vs $45,176; P<0.0001), higher mortality rate (8.5% vs 2.9%; P<0.0001), and higher colectomy rate (9.2% vs 5.9%; P<0.0001). Conclusion: CHF is associated with poor outcomes in patients with IC. Our study showed an increased risk of mortality and colectomy compared to patients with IC alone. The findings suggest it may be warranted to have a heightened clinical suspicion of IC in patients with CHF who present with bleeding per rectum. |
format | Online Article Text |
id | pubmed-9121910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-91219102022-05-21 Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study Mahfouz, Ratib Kozai, Landon A Obeidat, Adham E Darweesh, Mohammad Mansour, Mahmoud M Douglas, Mustafa F Berthiaume, Eric Cureus Cardiology Introduction: Ischemic colitis (IC) results from compromised blood flow to the colon. Risk factors include atrial fibrillation (A.Fib), peripheral artery disease (PAD), coronary artery disease (CAD), and congestive heart failure (CHF). However, few studies compared the mortality rate and colectomy between patients with IC with CHF and IC alone. Objective: We aim to investigate the possibility of worse outcomes in patients with IC and CHF compared to IC alone. Methodology: Using the National Inpatient Sample database from 2016 to 2019, we obtained baseline demographic data, total hospital charge, rate of colectomy, length of hospital stay (LOS), and in-hospital mortality. Data were compared using a t-test and chi-squared. Odds ratios for comorbidities including A.Fib, CAD, PAD, end-stage renal disease, chronic obstructive pulmonary disease, hyperlipidemia, hypertension, diabetes, and cirrhosis were calculated. Results: 106,705 patients with IC were identified, among which 15,220 patients also had CHF. IC patients with CHF had a longer LOS (6.6 days vs 4.4 days; P<0.0001), higher total hospital charge ($71,359 vs $45,176; P<0.0001), higher mortality rate (8.5% vs 2.9%; P<0.0001), and higher colectomy rate (9.2% vs 5.9%; P<0.0001). Conclusion: CHF is associated with poor outcomes in patients with IC. Our study showed an increased risk of mortality and colectomy compared to patients with IC alone. The findings suggest it may be warranted to have a heightened clinical suspicion of IC in patients with CHF who present with bleeding per rectum. Cureus 2022-04-20 /pmc/articles/PMC9121910/ /pubmed/35602840 http://dx.doi.org/10.7759/cureus.24308 Text en Copyright © 2022, Mahfouz et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Mahfouz, Ratib Kozai, Landon A Obeidat, Adham E Darweesh, Mohammad Mansour, Mahmoud M Douglas, Mustafa F Berthiaume, Eric Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title | Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title_full | Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title_fullStr | Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title_full_unstemmed | Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title_short | Congestive Heart Failure Is Associated With Worse Outcomes in Patients With Ischemic Colitis: A Nationwide Study |
title_sort | congestive heart failure is associated with worse outcomes in patients with ischemic colitis: a nationwide study |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121910/ https://www.ncbi.nlm.nih.gov/pubmed/35602840 http://dx.doi.org/10.7759/cureus.24308 |
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