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As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State

The COVID-19 pandemic has caused more than 448 million cases and 6 million deaths worldwide to date. Omicron is now the dominant SARS-CoV-2 variant, making up more than 90% of cases in countries reporting sequencing data. As the pandemic continues into its third year, continued testing is a strategi...

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Autores principales: Miller, Melissa B., Ooi, Eng Eong, Rhoads, Daniel D., Kulldorff, Martin, Anderson, Danielle E., Lee, Hyukmin, Gupta, Sunetra, Mel, Krajden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121917/
https://www.ncbi.nlm.nih.gov/pubmed/35602143
http://dx.doi.org/10.3389/fpubh.2022.883066
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author Miller, Melissa B.
Ooi, Eng Eong
Rhoads, Daniel D.
Kulldorff, Martin
Anderson, Danielle E.
Lee, Hyukmin
Gupta, Sunetra
Mel, Krajden
author_facet Miller, Melissa B.
Ooi, Eng Eong
Rhoads, Daniel D.
Kulldorff, Martin
Anderson, Danielle E.
Lee, Hyukmin
Gupta, Sunetra
Mel, Krajden
author_sort Miller, Melissa B.
collection PubMed
description The COVID-19 pandemic has caused more than 448 million cases and 6 million deaths worldwide to date. Omicron is now the dominant SARS-CoV-2 variant, making up more than 90% of cases in countries reporting sequencing data. As the pandemic continues into its third year, continued testing is a strategic and necessary tool for transitioning to an endemic state of COVID-19. Here, we address three critical topics pertaining to the transition from pandemic to endemic: defining the endemic state for COVID-19, highlighting the role of SARS-CoV-2 testing as endemicity is approached, and recommending parameters for SARS-CoV-2 testing once endemicity is reached. We argue for an approach that capitalizes on the current public health momentum to increase capacity for PCR-based testing and whole genome sequencing to monitor emerging infectious diseases. Strategic development and utilization of testing, including viral panels in addition to vaccination, can keep SARS-CoV-2 in a manageable endemic state and build a framework of preparedness for the next pandemic.
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spelling pubmed-91219172022-05-21 As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State Miller, Melissa B. Ooi, Eng Eong Rhoads, Daniel D. Kulldorff, Martin Anderson, Danielle E. Lee, Hyukmin Gupta, Sunetra Mel, Krajden Front Public Health Public Health The COVID-19 pandemic has caused more than 448 million cases and 6 million deaths worldwide to date. Omicron is now the dominant SARS-CoV-2 variant, making up more than 90% of cases in countries reporting sequencing data. As the pandemic continues into its third year, continued testing is a strategic and necessary tool for transitioning to an endemic state of COVID-19. Here, we address three critical topics pertaining to the transition from pandemic to endemic: defining the endemic state for COVID-19, highlighting the role of SARS-CoV-2 testing as endemicity is approached, and recommending parameters for SARS-CoV-2 testing once endemicity is reached. We argue for an approach that capitalizes on the current public health momentum to increase capacity for PCR-based testing and whole genome sequencing to monitor emerging infectious diseases. Strategic development and utilization of testing, including viral panels in addition to vaccination, can keep SARS-CoV-2 in a manageable endemic state and build a framework of preparedness for the next pandemic. Frontiers Media S.A. 2022-04-28 /pmc/articles/PMC9121917/ /pubmed/35602143 http://dx.doi.org/10.3389/fpubh.2022.883066 Text en Copyright © 2022 Miller, Ooi, Rhoads, Kulldorff, Anderson, Lee, Gupta and Mel. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Miller, Melissa B.
Ooi, Eng Eong
Rhoads, Daniel D.
Kulldorff, Martin
Anderson, Danielle E.
Lee, Hyukmin
Gupta, Sunetra
Mel, Krajden
As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title_full As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title_fullStr As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title_full_unstemmed As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title_short As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State
title_sort as omicron takes hold and other new variants arise, covid-19 testing remains the universally agreed tool to effect transition from pandemic to endemic state
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121917/
https://www.ncbi.nlm.nih.gov/pubmed/35602143
http://dx.doi.org/10.3389/fpubh.2022.883066
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