Cargando…

Hydrophilic Realgar Nanocrystals Prolong the Survival of Refractory Acute Myeloid Leukemia Mice Through Inducing Multi-Lineage Differentiation and Apoptosis

INTRODUCTION: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder of hematopoietic progenitor cells, and the AML cells are differentiation retarded which results in the hyperproliferation of those malignant tumor cells. To stop the uncontrollable proliferation, inducing the AML cell diff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Tao, Zhang, Xue, Jia, Mengfan, Yang, Aiyun, Liu, Jian, Wen, Tao, Meng, Jie, Xu, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122054/ https://www.ncbi.nlm.nih.gov/pubmed/35599749 http://dx.doi.org/10.2147/IJN.S358469

Ejemplares similares

Oral Realgar-Indigo Naturalis Formula Plus Retinoic Acid for Acute Promyelocytic Leukemia
por: Lou, Yinjun, et al.
Publicado: (2021)

Traditional mineral medicine realgar and Realgar-Indigo naturalis formula potentially exerted therapeutic effects by altering the gut microbiota
por: Luo, Lu, et al.
Publicado: (2023)

Sedative Hypnotic Activity of Manahshila (Realgar) -An Experimental Evaluation
por: Kodlady, Naveena, et al.
Publicado: (2011)

Enhanced antitumor activity of realgar mediated by milling it to nanosize
por: Tian, Ye, et al.
Publicado: (2014)

Pharmacology, Toxicology, and Rational Application of Cinnabar, Realgar, and Their Formulations
por: Guan, Huifang, et al.
Publicado: (2022)

Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells
por: Shi, Dan, et al.
Publicado: (2016)

Arsenic Accumulation of Realgar Altered by Disruption of Gut Microbiota in Mice
por: Xu, Wenfeng, et al.
Publicado: (2020)

Study on the Absorption of Arsenic Species in Realgar Based on the Form and Valence
por: Sun, Mingyi, et al.
Publicado: (2022)

Survival outcomes of children with relapsed or refractory myeloid leukemia associated with Down syndrome
por: Raghuram, Nikhil, et al.
Publicado: (2023)

(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia
por: Fang, Wei, et al.
Publicado: (2019)

Oral Realgar-Indigo Naturalis Formula Treatment for Acute Promyelocytic Leukemia in Children: A Randomized, Control Clinical Trial
por: Luo, Senlin, et al.
Publicado: (2022)

Inhibition of Murine Breast Cancer Metastases by Hydrophilic As(4)S(4) Nanoparticles Is Associated With Decreased ROS and HIF-1α Downregulation
por: Wang, Tao, et al.
Publicado: (2019)

Arsenic in Cancer Treatment: Challenges for Application of Realgar Nanoparticles (A Minireview)
por: Baláž, Peter, et al.
Publicado: (2010)

Preparation and characterization of realgar nanoparticles and their inhibitory effect on rat glioma cells
por: An, Yan-li, et al.
Publicado: (2011)

Treatment for Relapsed/Refractory Acute Myeloid Leukemia
por: Thol, Felicitas, et al.
Publicado: (2021)

A novel CD123-targeted therapeutic peptide loaded by micellar delivery system combats refractory acute myeloid leukemia
por: Xu, Shilin, et al.
Publicado: (2021)

Arsenic sulfide, the main component of realgar, a traditional Chinese medicine, induces apoptosis of gastric cancer cells in vitro and in vivo
por: Zhang, Lian, et al.
Publicado: (2014)

Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia
por: Sharma, Amit, et al.
Publicado: (2020)

TXNIP induces growth arrest and enhances ABT263‐induced apoptosis in mixed‐lineage leukemia‐rearranged acute myeloid leukemia cells
por: Noura, Mina, et al.
Publicado: (2020)

Effect of size and processing method on the cytotoxicity of realgar nanoparticles in cancer cell lines
por: Zhao, Weizhong, et al.
Publicado: (2011)

A Metabolic Profiling Study of Realgar-Induced Acute Kidney Injury in Mice
por: Zhang, Sheng, et al.
Publicado: (2021)

Hematopoietic and Chronic Myeloid Leukemia Stem Cells: Multi-Stability versus Lineage Restriction
por: Brown, Geoffrey
Publicado: (2022)

Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia
por: Ramchandren, Radhakrishnan, et al.
Publicado: (2009)

Pembrolizumab and decitabine for refractory or relapsed acute myeloid leukemia
por: Goswami, Meghali, et al.
Publicado: (2022)

Prolonged Survival of a Refractory Acute Myeloid Leukemia Patient after a Third Hematopoietic Stem Cell Transplantation with Umbilical Cord Blood following a Second Relapse
por: Lee, Suk-young, et al.
Publicado: (2014)

Philadelphia Chromosome-Positive Leukemia in the Lymphoid Lineage—Similarities and Differences with the Myeloid Lineage and Specific Vulnerabilities
por: Komorowski, Lukasz, et al.
Publicado: (2020)

Realgar-induced apoptosis and differentiation in all-trans retinoic acid (ATRA)-sensitive NB(4) and ATRA-resistant MR(2) cells
por: CHEN, SIYU, et al.
Publicado: (2011)

Apoptosis and necrosis induced by novel realgar quantum dots in human endometrial cancer cells via endoplasmic reticulum stress signaling pathway
por: Wang, Huan, et al.
Publicado: (2015)

Acute lymphoblastic leukemia to acute myeloid leukemia: an unusual case report of lineage switching
por: Pandit, Sudarshan, et al.
Publicado: (2022)

Myeloid Blast Crisis of Chronic Myeloid Leukemia Followed by Lineage Switch to B-Lymphoblastic Leukemia: A Case Report
por: Liu, Jiduo, et al.
Publicado: (2020)

Study on the Mechanism of Reducing Hepatotoxicity of Water-Grinding Realgar by Metabolomics, Morphology, and Chemical Analysis
por: Han, Ting, et al.
Publicado: (2021)

Xanthine oxidase, a therapeutic target of realgar for non-small cell lung cancer
por: Guo, Rui, et al.
Publicado: (2023)

Clinical Study on Prospective Efficacy of All-Trans Acid, Realgar-Indigo Naturalis Formula Combined with Chemotherapy as Maintenance Treatment of Acute Promyelocytic Leukemia
por: Xiang-Xin, Li, et al.
Publicado: (2014)

A stochastic model of myeloid cell lineages in hematopoiesis and pathway mutations in acute myeloid leukemia
por: Jäkel, Frank, et al.
Publicado: (2018)

IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival
por: Verhagen, H JMP, et al.
Publicado: (2014)

Use of cellular immunotherapy for treatment of refractory acute myeloid leukemia
por: Fast, Loren, et al.
Publicado: (2013)

Nonengraftment donor lymphocyte infusions for refractory acute myeloid leukemia
por: Reagan, J L, et al.
Publicado: (2015)

Current Approaches in the Treatment of Relapsed and Refractory Acute Myeloid Leukemia
por: Ramos, Nestor R., et al.
Publicado: (2015)

Venetoclax with Decitabine or Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia
por: Bouligny, Ian M., et al.
Publicado: (2023)

Myeloid lineage switch following CD7-targeted chimeric antigen receptor T-cell therapy in relapsed/refractory T-cell acute lymphoblastic leukemia
por: Aldoss, Ibrahim, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2dbb4vu5be65mfidnffg4r83ak