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Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents

Proteolytic targeting chimaeras (PROTACs) have been developed as an effective technology for targeted protein degradation. PROTACs are heterobifunctional molecules that can trigger the polyubiquitination of proteins of interest (POIs) by recruiting the ubiquitin-proteasome system, thereby inhibiting...

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Detalles Bibliográficos
Autores principales:	Wang, Chao, Zhang, Yujing, Shi, Lingyu, Yang, Shanbo, Chang, Jing, Zhong, Yingjie, Li, Qian, Xing, Dongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122363/ https://www.ncbi.nlm.nih.gov/pubmed/35589670 http://dx.doi.org/10.1080/14756366.2022.2074414

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