Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model

Alzheimer’s disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies targeting end-stage disease plaques, tangles, or inflammation have limited efficacy. Therefore, we set out to identify a potential earlier targ...

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Detalles Bibliográficos
Autores principales: Reinitz, Felicia, Chen, Elizabeth Y, Nicolis di Robilant, Benedetta, Chuluun, Bayarsaikhan, Antony, Jane, Jones, Robert C, Gubbi, Neha, Lee, Karen, Ho, William Hai Dang, Kolluru, Sai Saroja, Qian, Dalong, Adorno, Maddalena, Piltti, Katja, Anderson, Aileen, Monje, Michelle, Heller, H Craig, Quake, Stephen R, Clarke, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122497/
https://www.ncbi.nlm.nih.gov/pubmed/35311644
http://dx.doi.org/10.7554/eLife.66037

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