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The flexible N-terminal motif of uL11 unique to eukaryotic ribosomes interacts with P-complex and facilitates protein translation

Eukaryotic uL11 contains a conserved MPPKFDP motif at the N-terminus that is not found in archaeal and bacterial homologs. Here, we determined the solution structure of human uL11 by NMR spectroscopy and characterized its backbone dynamics by (15)N–(1)H relaxation experiments. We showed that these N...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Lee, Ka-Ming, Yu, Conny Wing-Heng, Imai, Hirotatsu, Choi, Andrew Kwok-Ho, Banfield, David K, Ito, Kosuke, Uchiumi, Toshio, Wong, Kam-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122527/
https://www.ncbi.nlm.nih.gov/pubmed/35544198
http://dx.doi.org/10.1093/nar/gkac292

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