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Novel eGZ-motif formed by regularly extruded guanine bases in a left-handed Z-DNA helix as a major motif behind CGG trinucleotide repeats

The expansion of d(CGG) trinucleotide repeats (TRs) lies behind several important neurodegenerative diseases. Atypical DNA secondary structures have been shown to trigger TR expansion: their characterization is important for a molecular understanding of TR disease. CD spectroscopy experiments in the...

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Detalles Bibliográficos
Autores principales:	Fakharzadeh, Ashkan, Zhang, Jiahui, Roland, Christopher, Sagui, Celeste
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122592/ https://www.ncbi.nlm.nih.gov/pubmed/35536254 http://dx.doi.org/10.1093/nar/gkac339

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