A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated enhancer clusters

As an oncogenic transcription factor, Yin Yang 1 (YY1) regulates enhancer and promoter connection. However, gaps still exist in understanding how YY1 coordinates coactivators and chromatin enhancer elements to assemble enhancers and super-enhancers. Here, we demonstrate that a histidine cluster in Y...

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Detalles Bibliográficos
Autores principales: Wang, Wenmeng, Qiao, Shiyao, Li, Guangyue, Cheng, Jiahui, Yang, Cuicui, Zhong, Chen, Stovall, Daniel B, Shi, Jinming, Teng, Chunbo, Li, Dangdang, Sui, Guangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122595/
https://www.ncbi.nlm.nih.gov/pubmed/35390165
http://dx.doi.org/10.1093/nar/gkac233

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