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Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain

The Dlk1-Dio3 imprinted domain is controlled by an imprinting control region (ICR) called IG-DMR that is hypomethylated on the maternal allele and hypermethylated on the paternal allele. Although several genetic mutation experiments have shown that IG-DMR is essential for imprinting control of the d...

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Detalles Bibliográficos
Autores principales:	Kojima, Shin, Shiochi, Naoya, Sato, Kazuki, Yamaura, Mamiko, Ito, Toshiaki, Yamamura, Nodoka, Goto, Naoki, Odamoto, Mika, Kobayashi, Shin, Kimura, Tohru, Sekita, Yoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122602/ https://www.ncbi.nlm.nih.gov/pubmed/35544282 http://dx.doi.org/10.1093/nar/gkac344

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