Targeting G-quadruplex DNA with synthetic dendritic peptide: modulation of the proliferation of human cancer cells

Telomerase, a reverse transcriptase enzyme, is found to over express in most cancer cells. It elongates the telomere region by repeated adding of TTAGGG in the 3′-end and leads to excess cell proliferation which causes cancer. G-quadruplex (G4) formation can inhibit such telomere lengthening. So, st...

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Detalles Bibliográficos
Autores principales: Biswas, Soumi, Samui, Satyabrata, Das, Apurba K., Pasadi, Sanjeev, Muniyappa, K., Naskar, Jishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122626/
https://www.ncbi.nlm.nih.gov/pubmed/35685402
http://dx.doi.org/10.1039/d0ra04780e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122626/
https://www.ncbi.nlm.nih.gov/pubmed/35685402
http://dx.doi.org/10.1039/d0ra04780e

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