Identification of Potential WSB1 Inhibitors by AlphaFold Modeling, Virtual Screening, and Molecular Dynamics Simulation Studies

WD40 repeat and SOCS box containing 1 (WSB1) consists of seven WD40 repeat structural domains at the N-terminal end and one SOCS box structural domain at the C-terminal end. WSB1 promotes cancer progression by affecting the Von Hippel–Lindau tumor suppressor protein (pVHL) and upregulating hypoxia i...

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Detalles Bibliográficos
Autores principales: Weng, Ye, Pan, Chenghao, Shen, Zheyuan, Chen, Sikang, Xu, Lei, Dong, Xiaowu, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122669/
https://www.ncbi.nlm.nih.gov/pubmed/35600960
http://dx.doi.org/10.1155/2022/4629392

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