Cargando…

Integrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome

OBJECTIVE: Bushen Huoxue Huatan Decoction (BHHD) is a classic prescription for treating polycystic ovary syndrome (PCOS). This study aims to explore the effects and possible mechanisms of BHHD on PCOS by integrating network pharmacology and clinical study. METHODS: The components and potential drug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Jie, Shanshan, Mei, Mengcheng, Cai, Danying, Zhang, Jin, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122682/ https://www.ncbi.nlm.nih.gov/pubmed/35600955 http://dx.doi.org/10.1155/2022/2635375

Ejemplares similares

The Ameliorating Effects of Bushen Huatan Granules and Kunling Wan on Polycystic Ovary Syndrome Induced by Dehydroepiandrosterone in Rats
por: Xu, Yang, et al.
Publicado: (2021)

Efficacy of Bushen Huatan Decoction combined with Baduanjin in the treatment of polycystic ovary syndrome with insulin resistance (IR-PCOS), kidney deficiency and phlegm dampness: study protocol for a randomized controlled trial
por: Qian, Haiqing, et al.
Publicado: (2021)

Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments
por: Huang, Hong-Tao, et al.
Publicado: (2023)

The Effectiveness and Safety of Bushen Huoxue Decoction on Treating Coronary Heart Disease: A Meta-Analysis
por: Liu, Lan-Chun, et al.
Publicado: (2021)

LC-MS/MS analysis and evaluation of the anti-inflammatory activity of components from BushenHuoxue decoction
por: Sun, Dongdong, et al.
Publicado: (2017)

Mechanisms of the Bushen Huoxue formula in the treatment of osteoarthritis based on network pharmacology-molecular targets
por: Pang, Tingting, et al.
Publicado: (2022)

Bushen Huoxue formula for the treatment of diminished ovarian reserve: A combined metabolomics and integrated network pharmacology analysis
por: Zeng, Pengfei, et al.
Publicado: (2023)

Wnt5a mediates the effects of Bushen Huoxue decoction on the migration of bone marrow mesenchymal stem cells in vitro
por: Shen, Wei, et al.
Publicado: (2018)

Network pharmacology and experimental validation to explore the molecular mechanisms of Bushen Huoxue for the treatment of premature ovarian insufficiency
por: Cao, Ying, et al.
Publicado: (2021)

Meta-Analysis of Chinese Traditional Medicine Bushen Huoxue Prescription for Endometriosis Treatment
por: Shan, Jing, et al.
Publicado: (2017)

Network-Based Pharmacological Study on the Mechanism of Action of Buxue Liqi Huatan Decoction in the Treatment of Lung Cancer
por: Wei, Huabing, et al.
Publicado: (2022)

Efficacy of clomifene citrate combined Bushen Culuan Decoction for the treatment of infertility caused by polycystic ovary syndrome: A protocol of systematic review
por: Feng, Jing, et al.
Publicado: (2020)

BushenHuoxue decoction suppresses M1 macrophage polarization and prevents LPS induced inflammatory bone loss by activating AMPK pathway
por: Chen, Shuangshuang, et al.
Publicado: (2023)

Based on Network Pharmacology and RNA Sequencing Techniques to Explore the Molecular Mechanism of Huatan Jiangzhuo Decoction for Treating Hyperlipidemia
por: Zhou, Xiaowen, et al.
Publicado: (2021)

Huoxue Huatan Decoction Ameliorates Myocardial Ischemia/Reperfusion Injury in Hyperlipidemic Rats via PGC-1α–PPARα and PGC-1α–NRF1–mtTFA Pathways
por: Lin, Fei, et al.
Publicado: (2020)

Network Pharmacology-Based Study on the Mechanism of Bushen-Jianpi Decoction in Liver Cancer Treatment
por: Wu, Rong, et al.
Publicado: (2019)

Past and present: a bibliometric study on polycystic ovary syndrome
por: Cai, Mengcheng, et al.
Publicado: (2023)

MiR-539-5p negatively regulates migration of rMSCs induced by Bushen Huoxue decoction through targeting Wnt5a
por: Hu, Liuchao, et al.
Publicado: (2019)

Bushen huoxue decoction inhibits RANKL-stimulated osteoclastogenesis and glucocorticoid-induced bone loss by modulating the NF-κB, ERK, and JNK signaling pathways
por: Liu, Yamei, et al.
Publicado: (2022)

BuShen HuoXue decoction improves fertility through intestinal hsp-16.2-mediated heat-shock signaling pathway in Caenorhabditis elegans
por: Wu, Kanglu, et al.
Publicado: (2023)

A Study of the Protective Effect of Bushen Huoxue Prescription on Cerebral Microvascular Endothelia Based on Proteomics and Bioinformatics
por: Zhao, Shao-Yang, et al.
Publicado: (2022)

The effect of Bushen Huoxue method in treating glaucoma: A protocol for systematic review and meta-analysis
por: Wang, Liyuan, et al.
Publicado: (2020)

Effects of bushen huoxue method for knee osteoarthritis: A protocol for systematic review and meta-analysis
por: Chen, Guocai, et al.
Publicado: (2020)

Effect of Bushen Huoxue Prescription on Cognitive Dysfunction of KK-Ay Type 2 Diabetic Mice
por: Zhao, Shao-Yang, et al.
Publicado: (2021)

BuShen HuoXue Decoction Promotes Decidual Stromal Cell Proliferation via the PI3K/AKT Pathway in Unexplained Recurrent Spontaneous Abortion
por: Feng, Xiaoling, et al.
Publicado: (2020)

Corrigendum: Bushen huoxue decoction inhibits RANKL-stimulated osteoclastogenesis and glucocorticoid-induced bone loss by modulating the NF-κB, ERK, and JNK signaling pathways
por: Liu, Yamei, et al.
Publicado: (2023)

Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Bushen Huashi decoction against kidney stones
por: Liu, Haizhao, et al.
Publicado: (2023)

Network pharmacological analysis of active components of Tongqiao Huoxue Decoction in the treatment of intracerebral hemorrhage
por: Wu, Ji, et al.
Publicado: (2022)

Potential Molecular Mechanism of Guishen Huoxue Decoction against Intrauterine Adhesion Based on Network Pharmacology
por: Zhang, Wenyan, et al.
Publicado: (2022)

A network pharmacology approach to explore the mechanisms of Erxian decoction in polycystic ovary syndrome
por: Liu, Lihong, et al.
Publicado: (2018)

Effects of Bushen Huoxue method for female with decreased ovarian reserve: A protocol for systematic review and meta-analysis
por: Xie, Zhuoting, et al.
Publicado: (2020)

Chinese Herbs Medicine Huatan Huoxue Prescription for obstructive sleep apnea hypopnea syndrome as complementary therapy: A protocol for a systematic review and meta-analysis
por: Zhou, Min, et al.
Publicado: (2020)

Mechanism of Huoxue Tongluo Decoction in treatment of erectile dysfunction caused by ischemic stroke based on network pharmacology
por: Wang, Ji-sheng, et al.
Publicado: (2021)

Pharmacokinetics and tissue distribution study of tanshinone IIA after oral administration of Bushen Huoxue Qubi granules to rats with blood stasis syndrome
por: Wang, Yuanqing, et al.
Publicado: (2014)

Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice
por: Song, Yufan, et al.
Publicado: (2021)

Integrated UPLC-MS and Network Pharmacology Approach to Explore the Active Components and the Potential Mechanism of Yiqi Huoxue Decoction for Treating Nephrotic Syndrome
por: Feng, Dan, et al.
Publicado: (2022)

Prediction of the mechanisms of action of Qutan Huoxue decoction in non-alcoholic steatohepatitis (NASH): a network pharmacology study and experimental validation
por: Wu, Xia, et al.
Publicado: (2023)

Bushen Huoxue Acupuncture Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in SAMP8 Mouse Model of Alzheimer’s Disease
por: Zhang, Ting, et al.
Publicado: (2021)

BushenHuoxue Recipe for the Treatment of Prethrombotic State of ACA-Positive Recurrent Miscarriage via the Regulation of the PI3K-AKT Signaling Pathway
por: Yang, Xuan, et al.
Publicado: (2022)

Understanding the diverse functions of Huatan Tongluo Fang on rheumatoid arthritis from a pharmacological perspective
por: ZHENG, CHUNSONG, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_o2cg9oaih4htap33bodtfdd6k8