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Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
Glioblastoma is the most prevalent primary malignant brain tumor in adults and is characterized by poor prognosis and universal tumor recurrence. Effective glioblastoma treatments are lacking, in part due to somatic mutations and epigenetic reprogramming that alter gene expression and confer drug re...
Autores principales: | Sen, Arko, Prager, Briana C., Zhong, Cuiqing, Park, Donglim, Zhu, Zhe, Gimple, Ryan C., Wu, Qiulian, Bernatchez, Jean A., Beck, Sungjun, Clark, Alex E., Siqueira-Neto, Jair L., Rich, Jeremy N., McVicker, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122831/ https://www.ncbi.nlm.nih.gov/pubmed/34903607 http://dx.doi.org/10.1158/0008-5472.CAN-21-0810 |
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