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Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles

Colorectal cancer (CRC) with a mesenchymal gene expression signature has the greatest propensity for distant metastasis and is characterised by the accumulation of cancer‐associated fibroblasts in the stroma. We investigated whether the epithelial to mesenchymal transition status of CRC cells influe...

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Detalles Bibliográficos
Autores principales: Bhome, Rahul, Emaduddin, Muhammad, James, Victoria, House, Louise M., Thirdborough, Stephen M., Mellone, Massimiliano, Tulkens, Joeri, Primrose, John N., Thomas, Gareth J., De Wever, Olivier, Mirnezami, Alex H., Sayan, A. Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122835/
https://www.ncbi.nlm.nih.gov/pubmed/35595718
http://dx.doi.org/10.1002/jev2.12226