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Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles
Colorectal cancer (CRC) with a mesenchymal gene expression signature has the greatest propensity for distant metastasis and is characterised by the accumulation of cancer‐associated fibroblasts in the stroma. We investigated whether the epithelial to mesenchymal transition status of CRC cells influe...
Autores principales: | Bhome, Rahul, Emaduddin, Muhammad, James, Victoria, House, Louise M., Thirdborough, Stephen M., Mellone, Massimiliano, Tulkens, Joeri, Primrose, John N., Thomas, Gareth J., De Wever, Olivier, Mirnezami, Alex H., Sayan, A. Emre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122835/ https://www.ncbi.nlm.nih.gov/pubmed/35595718 http://dx.doi.org/10.1002/jev2.12226 |
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