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Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Chemotherapy is a standard therapy for muscle-invasive bladder cancer (MIBC). However, genomic alterations associated with chemotherapy sensitivity in MIBC have not been fully explored. This study aimed to investigate the genomic landscape of MIBC in association with the response to chemotherapy and...

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Detalles Bibliográficos
Autores principales:	Tsukahara, Shigehiro, Shiota, Masaki, Takamatsu, Dai, Nagakawa, Shohei, Matsumoto, Takashi, Kiyokoba, Ryo, Yagi, Mikako, Setoyama, Daiki, Noda, Nozomi, Matsumoto, Shinya, Hayashi, Tetsutaro, Contreras-Sanz, Alberto, Black, Peter C., Inokuchi, Junichi, Kohashi, Kenichi, Oda, Yoshinao, Uchiumi, Takeshi, Eto, Masatoshi, Kang, Dongchon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122908/ https://www.ncbi.nlm.nih.gov/pubmed/35595780 http://dx.doi.org/10.1038/s41598-022-12528-3

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