Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity

Mounting evidence suggests the key role of brain-derived neurotrophic factor (BDNF) in the dopaminergic neurotoxicity of Parkinson’s disease (PD). Activation of NF-E2-related factor-2 (Nrf2) and inhibition of methyl CpG-binding protein 2 (MeCP2) can regulate BDNF upregulation. However, the regulatio...

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Detalles Bibliográficos
Autores principales: Cao, Qianqian, Zou, Qiuming, Zhao, Xin, Zhang, Yimin, Qu, Youge, Wang, Nanbu, Murayama, Shigeo, Qi, Qi, Hashimoto, Kenji, Lin, Song, Zhang, Ji-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122988/
https://www.ncbi.nlm.nih.gov/pubmed/35595779
http://dx.doi.org/10.1038/s41420-022-01063-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122988/
https://www.ncbi.nlm.nih.gov/pubmed/35595779
http://dx.doi.org/10.1038/s41420-022-01063-9

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