Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques

Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification...

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Autores principales: Haese, Matteo, Winterhalter, Kai, Jung, Jessica, Schmidt, Magnus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123081/
https://www.ncbi.nlm.nih.gov/pubmed/35595946
http://dx.doi.org/10.1007/s41061-022-00383-9
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author Haese, Matteo
Winterhalter, Kai
Jung, Jessica
Schmidt, Magnus S.
author_facet Haese, Matteo
Winterhalter, Kai
Jung, Jessica
Schmidt, Magnus S.
author_sort Haese, Matteo
collection PubMed
description Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification of the method have continued since its discovery by Emil Fischer in the 1890s. This review presents advancements in Fischer glycosylation described in literature of the past 15 years and its implementation in modern chemical methods.
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spelling pubmed-91230812022-05-22 Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques Haese, Matteo Winterhalter, Kai Jung, Jessica Schmidt, Magnus S. Top Curr Chem (Cham) Review Fischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification of the method have continued since its discovery by Emil Fischer in the 1890s. This review presents advancements in Fischer glycosylation described in literature of the past 15 years and its implementation in modern chemical methods. Springer International Publishing 2022-05-21 2022 /pmc/articles/PMC9123081/ /pubmed/35595946 http://dx.doi.org/10.1007/s41061-022-00383-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Haese, Matteo
Winterhalter, Kai
Jung, Jessica
Schmidt, Magnus S.
Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title_full Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title_fullStr Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title_full_unstemmed Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title_short Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
title_sort like visiting an old friend: fischer glycosylation in the twenty-first century: modern methods and techniques
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123081/
https://www.ncbi.nlm.nih.gov/pubmed/35595946
http://dx.doi.org/10.1007/s41061-022-00383-9
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