Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways

Microtubule targeting agents (MTAs) are widely used cancer chemotherapeutics which conventionally exert their effects during mitosis, leading to mitotic or postmitotic death. However, accumulating evidence suggests that MTAs can also generate death signals during interphase, which may represent a ke...

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Detalles Bibliográficos
Autores principales: Delgado, Magdalena, Rainwater, Randall R., Heflin, Billie, Urbaniak, Alicja, Butler, Kaitlynn, Davidson, Mari, Protacio, Reine M., Baldini, Giulia, Edwards, Andrea, Reed, Megan R., Raney, Kevin D., Chambers, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123221/
https://www.ncbi.nlm.nih.gov/pubmed/35436470
http://dx.doi.org/10.1016/j.jbc.2022.101939

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