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Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway

The guided entry of tail-anchored proteins (GET) pathway targets C-terminally anchored transmembrane proteins and protects cells from lipotoxicity. Here, we reveal perturbed ergosterol production in ∆get3 cells and demonstrate the sensitivity of GET pathway mutants to the sterol synthesis inhibiting...

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Detalles Bibliográficos
Autores principales:	Farkas, Ákos, Urlaub, Henning, Bohnsack, Katherine E., Schwappach, Blanche
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123286/ https://www.ncbi.nlm.nih.gov/pubmed/35587358 http://dx.doi.org/10.1083/jcb.202201036

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