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Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population

Skeletal muscle mass and muscle strength are positively correlated, but the relationship between grip strength and global muscle strength is controversial. This study aimed to clarify the changes in site-specific skeletal muscle mass by age group and determine the relationship between site-specific,...

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Autores principales: Iwase, Hiroaki, Murata, Shin, Nakano, Hideki, Shiraiwa, Kayoko, Abiko, Teppei, Goda, Akio, Nonaka, Koji, Anami, Kunihiko, Horie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123344/
https://www.ncbi.nlm.nih.gov/pubmed/35607534
http://dx.doi.org/10.7759/cureus.24260
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author Iwase, Hiroaki
Murata, Shin
Nakano, Hideki
Shiraiwa, Kayoko
Abiko, Teppei
Goda, Akio
Nonaka, Koji
Anami, Kunihiko
Horie, Jun
author_facet Iwase, Hiroaki
Murata, Shin
Nakano, Hideki
Shiraiwa, Kayoko
Abiko, Teppei
Goda, Akio
Nonaka, Koji
Anami, Kunihiko
Horie, Jun
author_sort Iwase, Hiroaki
collection PubMed
description Skeletal muscle mass and muscle strength are positively correlated, but the relationship between grip strength and global muscle strength is controversial. This study aimed to clarify the changes in site-specific skeletal muscle mass by age group and determine the relationship between site-specific, age-related changes in skeletal muscle mass and physical function in community-dwelling elderly people in Japan. The participants were divided into age groups of five-year intervals (65-69 years, 70-74 years, 75-79 years, and ≥80 years) and were also categorized by sex. The skeletal muscle mass of the upper limbs, lower limbs, and trunk was measured using multifrequency bioelectrical impedance analyzers (InBody 430 (Biospace Co., Ltd., Seoul, Korea) and InBody 470 (InBody Japan Inc., Tokyo, Japan)). For physical function assessment, we measured grip strength, quadriceps strength, sit-up count, sit-and-reach distance, and standing time on one leg with eyes open and performed the timed up and go (TUG) test. The results showed that skeletal muscle mass decreased with age regardless of sex at all measured sites. Furthermore, a partial correlation analysis adjusted for age, physical constitution, and the presence/absence of exercise habits revealed that the highest correlation was between skeletal muscle mass in all sites and grip strength. Thus, monitoring grip strength may be used as a representative of systemic skeletal mass even in Japanese people.
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spelling pubmed-91233442022-05-22 Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population Iwase, Hiroaki Murata, Shin Nakano, Hideki Shiraiwa, Kayoko Abiko, Teppei Goda, Akio Nonaka, Koji Anami, Kunihiko Horie, Jun Cureus Physical Medicine & Rehabilitation Skeletal muscle mass and muscle strength are positively correlated, but the relationship between grip strength and global muscle strength is controversial. This study aimed to clarify the changes in site-specific skeletal muscle mass by age group and determine the relationship between site-specific, age-related changes in skeletal muscle mass and physical function in community-dwelling elderly people in Japan. The participants were divided into age groups of five-year intervals (65-69 years, 70-74 years, 75-79 years, and ≥80 years) and were also categorized by sex. The skeletal muscle mass of the upper limbs, lower limbs, and trunk was measured using multifrequency bioelectrical impedance analyzers (InBody 430 (Biospace Co., Ltd., Seoul, Korea) and InBody 470 (InBody Japan Inc., Tokyo, Japan)). For physical function assessment, we measured grip strength, quadriceps strength, sit-up count, sit-and-reach distance, and standing time on one leg with eyes open and performed the timed up and go (TUG) test. The results showed that skeletal muscle mass decreased with age regardless of sex at all measured sites. Furthermore, a partial correlation analysis adjusted for age, physical constitution, and the presence/absence of exercise habits revealed that the highest correlation was between skeletal muscle mass in all sites and grip strength. Thus, monitoring grip strength may be used as a representative of systemic skeletal mass even in Japanese people. Cureus 2022-04-18 /pmc/articles/PMC9123344/ /pubmed/35607534 http://dx.doi.org/10.7759/cureus.24260 Text en Copyright © 2022, Iwase et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Physical Medicine & Rehabilitation
Iwase, Hiroaki
Murata, Shin
Nakano, Hideki
Shiraiwa, Kayoko
Abiko, Teppei
Goda, Akio
Nonaka, Koji
Anami, Kunihiko
Horie, Jun
Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title_full Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title_fullStr Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title_full_unstemmed Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title_short Relationship Between Age-Related Changes in Skeletal Muscle Mass and Physical Function: A Cross-Sectional Study of an Elderly Japanese Population
title_sort relationship between age-related changes in skeletal muscle mass and physical function: a cross-sectional study of an elderly japanese population
topic Physical Medicine & Rehabilitation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123344/
https://www.ncbi.nlm.nih.gov/pubmed/35607534
http://dx.doi.org/10.7759/cureus.24260
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