Cargando…

Prevalence of Germline Findings Among Tumors From Cancer Types Lacking Hereditary Testing Guidelines

IMPORTANCE: Germline testing guidelines are suggested for specific disease types or a family history of cancer, yet alterations are found in cancer types in which germline testing is not routinely indicated. The clinical role of identifying germline variants in these populations is valuable to patie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yap, Timothy A., Ashok, Arya, Stoll, Jessica, Mauer, Elizabeth, Nepomuceno, Vanessa M., Blackwell, Kimberly L., Garber, Judy E., Meric-Bernstam, Funda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123503/ https://www.ncbi.nlm.nih.gov/pubmed/35594047 http://dx.doi.org/10.1001/jamanetworkopen.2022.13070

Ejemplares similares

Coordinated prophylactic surgical management for women with hereditary breast-ovarian cancer syndrome
por: Batista, Larissa I, et al.
Publicado: (2008)

Universal Germline Genetic Testing for Hereditary Cancer Syndromes in Patients With Solid Tumor Cancer
por: Esplin, Edward D., et al.
Publicado: (2022)

Whole Genome Sequencing in Cancer Clinics
por: Chen, Ken, et al.
Publicado: (2014)

Personalized cancer therapy—leveraging a knowledge base for clinical decision-making
por: Dumbrava, Ecaterina Ileana, et al.
Publicado: (2018)

Antibody-drug conjugates in lung cancer: dawn of a new era?
por: Coleman, Niamh, et al.
Publicado: (2023)

Comparison of Real-Time Fluorescence Confocal Digital Microscopy With Hematoxylin-Eosin–Stained Sections of Core-Needle Biopsy Specimens
por: Krishnamurthy, Savitri, et al.
Publicado: (2020)

Targeting translation initiation in breast cancer
por: Akcakanat, Argun, et al.
Publicado: (2014)

A Germline Clone Screen on the X Chromosome Reveals Novel Meiotic Mutants in Drosophila melanogaster
por: Collins, Kimberly A., et al.
Publicado: (2012)

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers
por: van der Post, Rachel S, et al.
Publicado: (2015)

Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis
por: Kratz, Christian P., et al.
Publicado: (2021)

Two Classes of Gap Junction Channels Mediate Soma-Germline Interactions Essential for Germline Proliferation and Gametogenesis in Caenorhabditis elegans
por: Starich, Todd A., et al.
Publicado: (2014)

Germline Fitness-Based Scoring of Cancer Mutations
por: Fischer, Andrej, et al.
Publicado: (2011)

Contrasting Determinants of Mutation Rates in Germline and Soma
por: Chen, Chen, et al.
Publicado: (2017)

Adaptive Evolution of Genes Involved in the Regulation of Germline Stem Cells in Drosophila melanogaster and D. simulans
por: Flores, Heather A., et al.
Publicado: (2015)

Maternal Germline-Specific Genes in the Asian Malaria Mosquito Anopheles stephensi: Characterization and Application for Disease Control
por: Biedler, James K., et al.
Publicado: (2014)

Homology-Dependent Silencing by an Exogenous Sequence in the Drosophila Germline
por: Pöyhönen, Maria, et al.
Publicado: (2012)

Transcribed germline-limited coding sequences in Oxytricha trifallax
por: Miller, Richard V, et al.
Publicado: (2021)

Germline progenitors and oocyte production in the honeybee queen ovary
por: Cullen, Georgia, et al.
Publicado: (2023)

The rapamycin-regulated gene expression signature determines prognosis for breast cancer
por: Akcakanat, Argun, et al.
Publicado: (2009)

Response to Mammalian Target of Rapamycin–Based Therapy and Incidental Finding of Lynch Syndrome in a Patient With Solid Pseudopapillary Neoplasm of the Pancreas With AKT1_E17K Mutation
por: Cuglievan, Branko, et al.
Publicado: (2018)

Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline
por: Reichman, Rachel, et al.
Publicado: (2018)

Pheochromocytoma and paraganglioma: germline genetics and hereditary syndromes
por: Turin, Christie G, et al.
Publicado: (2022)

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance
por: Lebo, Diane P V, et al.
Publicado: (2021)

Longitudinal Analysis of Cancer Risk in Children and Adults With Germline PTEN Variants
por: Yehia, Lamis, et al.
Publicado: (2023)

Automated and customizable quantitative image analysis of whole Caenorhabditis elegans germlines
por: Toraason, Erik, et al.
Publicado: (2021)

Type-I Prenyl Protease Function Is Required in the Male Germline of Drosophila melanogaster
por: Adolphsen, Katie, et al.
Publicado: (2012)

Germline Variants in the POT1-Gene in High-Risk Melanoma Patients in Austria
por: Müller, Christoph, et al.
Publicado: (2018)

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans
por: Lissemore, James L., et al.
Publicado: (2018)

The Impact of DNA Methylation Dynamics on the Mutation Rate During Human Germline Development
por: Zhou, Yijia, et al.
Publicado: (2020)

Mutation, selection, and the prevalence of the Caenorhabditis elegans heat-sensitive mortal germline phenotype
por: Saber, Sayran, et al.
Publicado: (2022)

Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel
por: Shen, Chan, et al.
Publicado: (2016)

PUF-8, a Pumilio Homolog, Inhibits the Proliferative Fate in the Caenorhabditis elegans Germline
por: Racher, Hilary, et al.
Publicado: (2012)

From Embryo to Adult: piRNA-Mediated Silencing throughout Germline Development in Drosophila
por: Marie, Pauline P., et al.
Publicado: (2016)

Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila
por: Shukla, Vallari, et al.
Publicado: (2018)

Toward Identifying Subnetworks from FBF Binding Landscapes in Caenorhabditis Spermatogenic or Oogenic Germlines
por: Porter, Douglas F., et al.
Publicado: (2018)

Germline Proliferation Is Regulated by Somatic Endocytic Genes via JNK and BMP Signaling in Drosophila
por: Tang, Yaning, et al.
Publicado: (2017)

Mutator Foci Are Regulated by Developmental Stage, RNA, and the Germline Cell Cycle in Caenorhabditis elegans
por: Uebel, Celja J., et al.
Publicado: (2020)

Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules
por: Marnik, Elisabeth A., et al.
Publicado: (2019)

Efficacy of Quality Criteria to Identify Potentially Harmful Information: A Cross-sectional Survey of Complementary and Alternative Medicine Web Sites
por: Walji, Muhammad, et al.
Publicado: (2004)

Lack of compliance: a challenge for digital dermoscopy follow-up()
por: Gadens, Guilherme Augusto
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kqan1v0p6r1c3a1te27oblv94d