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Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

PURPOSE: To investigate how cataract-linked mutations affect the gradient refractive index (GRIN) and lens opacification in mouse lenses and whether there is any effect on the optics of the lens from treatment with an oxysterol compound. METHODS: A total of 35 mice including wild-type and knock-in m...

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Detalles Bibliográficos
Autores principales:	Wang, Kehao, Hoshino, Masato, Uesugi, Kentaro, Yagi, Naoto, Pierscionek, Barbara K., Andley, Usha P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Lens
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123516/ https://www.ncbi.nlm.nih.gov/pubmed/35575904 http://dx.doi.org/10.1167/iovs.63.5.15

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