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Therapeutic impact of determination of RAS mutations in the plasma of patient with colorectal cancer

Stage IV colorectal cancer treatment includes targeted therapy depending on RAS status. During disease progression, loss or gain of RAS mutations could happen, supporting the hypothesis of the evolutionary pressure of therapy. Circulating tumor DNA (ctDNA) are nucleic acids released to the bloodstre...

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Detalles Bibliográficos
Autores principales: Macedo, F, Monteiro, J, Pereira, T. Cunha, Monteiro, A.R., Felix Soares, R., Bonito, N, Sousa, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123636/
https://www.ncbi.nlm.nih.gov/pubmed/35611253