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KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription

BACKGROUND: This study aims to clarify the mechanistic action of long non-coding RNA (lncRNA) SNHG12 in the development of renal cell carcinoma (RCC), which may be associated with promoter methylation modification by KMT2B and the regulation of the E2F1/CEP55 axis. METHODS: TCGA and GEO databases we...

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Detalles Bibliográficos
Autores principales: Feng, Jia-fu, Wang, Jun, Xie, Gang, Wang, Yao-dong, Li, Xiao-han, Yang, Wen-yu, Yang, Yu-wei, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123657/
https://www.ncbi.nlm.nih.gov/pubmed/35597996
http://dx.doi.org/10.1186/s12935-022-02607-w

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