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P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells

BACKGROUND: P-selectin glycoprotein ligand-1 (PSGL-1/CD162) has been studied extensively for its role in mediating leukocyte rolling through interactions with its cognate receptor, P-selectin. Recently, PSGL-1 was identified as a novel HIV-1 host restriction factor, particularly when expressed at hi...

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Detalles Bibliográficos
Autores principales: Burnie, Jonathan, Persaud, Arvin Tejnarine, Thaya, Laxshaginee, Liu, Qingbo, Miao, Huiyi, Grabinsky, Stephen, Norouzi, Vanessa, Lusso, Paolo, Tang, Vera A., Guzzo, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123692/
https://www.ncbi.nlm.nih.gov/pubmed/35597982
http://dx.doi.org/10.1186/s12977-022-00593-5