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P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells
BACKGROUND: P-selectin glycoprotein ligand-1 (PSGL-1/CD162) has been studied extensively for its role in mediating leukocyte rolling through interactions with its cognate receptor, P-selectin. Recently, PSGL-1 was identified as a novel HIV-1 host restriction factor, particularly when expressed at hi...
Autores principales: | Burnie, Jonathan, Persaud, Arvin Tejnarine, Thaya, Laxshaginee, Liu, Qingbo, Miao, Huiyi, Grabinsky, Stephen, Norouzi, Vanessa, Lusso, Paolo, Tang, Vera A., Guzzo, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123692/ https://www.ncbi.nlm.nih.gov/pubmed/35597982 http://dx.doi.org/10.1186/s12977-022-00593-5 |
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