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Introduction of salvage prostatectomy in Denmark: the initial experience

OBJECTIVE: To introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following radiation therapy existed in Denmark. This pilot study represent our initial experiences and the feasibility of performing salvage robot-assisted radical pr...

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Autores principales: Mortensen, Mike Allan, Poulsen, Charlotte Aaberg, Ahlgren, Göran, Madsen, Kirsten, Poulsen, Mads Hvid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123700/
https://www.ncbi.nlm.nih.gov/pubmed/35597969
http://dx.doi.org/10.1186/s13104-022-06076-2
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author Mortensen, Mike Allan
Poulsen, Charlotte Aaberg
Ahlgren, Göran
Madsen, Kirsten
Poulsen, Mads Hvid
author_facet Mortensen, Mike Allan
Poulsen, Charlotte Aaberg
Ahlgren, Göran
Madsen, Kirsten
Poulsen, Mads Hvid
author_sort Mortensen, Mike Allan
collection PubMed
description OBJECTIVE: To introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following radiation therapy existed in Denmark. This pilot study represent our initial experiences and the feasibility of performing salvage robot-assisted radical prostatectomy for true local, high-risk recurrence after initial therapy with external beam radiation for high-risk prostate cancer. RESULTS: Five patients underwent sRARP between April 2020 and July 2021. All patients were discharged within 48 h and no major complications were observed within 3 months. All patients had unmeasurable PSA (< 0.1 ng/ml) at follow-up 6 months after surgery. One patient with longer follow-up than 6 months experienced biochemical recurrence. At 3-months follow-up all patients reported considerable incontinence, at 6-month follow-up, pad usage decreased to 1 or 2 pads daily. Based on our initial results, the idea to introduce sRARP as a nationwide option remains and further patients will be included to establish the true role of sRARP in patients with recurrence after primary radiotherapy for PCa.
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spelling pubmed-91237002022-05-22 Introduction of salvage prostatectomy in Denmark: the initial experience Mortensen, Mike Allan Poulsen, Charlotte Aaberg Ahlgren, Göran Madsen, Kirsten Poulsen, Mads Hvid BMC Res Notes Research Note OBJECTIVE: To introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following radiation therapy existed in Denmark. This pilot study represent our initial experiences and the feasibility of performing salvage robot-assisted radical prostatectomy for true local, high-risk recurrence after initial therapy with external beam radiation for high-risk prostate cancer. RESULTS: Five patients underwent sRARP between April 2020 and July 2021. All patients were discharged within 48 h and no major complications were observed within 3 months. All patients had unmeasurable PSA (< 0.1 ng/ml) at follow-up 6 months after surgery. One patient with longer follow-up than 6 months experienced biochemical recurrence. At 3-months follow-up all patients reported considerable incontinence, at 6-month follow-up, pad usage decreased to 1 or 2 pads daily. Based on our initial results, the idea to introduce sRARP as a nationwide option remains and further patients will be included to establish the true role of sRARP in patients with recurrence after primary radiotherapy for PCa. BioMed Central 2022-05-21 /pmc/articles/PMC9123700/ /pubmed/35597969 http://dx.doi.org/10.1186/s13104-022-06076-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Mortensen, Mike Allan
Poulsen, Charlotte Aaberg
Ahlgren, Göran
Madsen, Kirsten
Poulsen, Mads Hvid
Introduction of salvage prostatectomy in Denmark: the initial experience
title Introduction of salvage prostatectomy in Denmark: the initial experience
title_full Introduction of salvage prostatectomy in Denmark: the initial experience
title_fullStr Introduction of salvage prostatectomy in Denmark: the initial experience
title_full_unstemmed Introduction of salvage prostatectomy in Denmark: the initial experience
title_short Introduction of salvage prostatectomy in Denmark: the initial experience
title_sort introduction of salvage prostatectomy in denmark: the initial experience
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123700/
https://www.ncbi.nlm.nih.gov/pubmed/35597969
http://dx.doi.org/10.1186/s13104-022-06076-2
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