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StaRTrEK:in silico estimation of RNA half-lives from genome-wide time-course experiments without transcriptional inhibition

BACKGROUND: Gene expression is the result of the balance between transcription and degradation. Recent experimental findings have shown fine and specific regulation of RNA degradation and the presence of various molecular machinery purposely devoted to this task, such as RNA binding proteins, non-co...

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Detalles Bibliográficos
Autores principales: Conte, Federica, Papa, Federico, Paci, Paola, Farina, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123730/
https://www.ncbi.nlm.nih.gov/pubmed/35596139
http://dx.doi.org/10.1186/s12859-022-04730-x