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A new day for human challenge trials?

Two years into the coronavirus disease 2019 (COVID-19) pandemic and following several hot debates, the world’s first COVID-19 human challenge trial has recently been published by Killingley et al. We review its findings and explain why this particular juncture in time makes additional challenge tria...

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Detalles Bibliográficos
Autores principales: Rohrig, Abie, Eyal, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124157/
https://www.ncbi.nlm.nih.gov/pubmed/35610124
http://dx.doi.org/10.1016/j.molmed.2022.05.002
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author Rohrig, Abie
Eyal, Nir
author_facet Rohrig, Abie
Eyal, Nir
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description Two years into the coronavirus disease 2019 (COVID-19) pandemic and following several hot debates, the world’s first COVID-19 human challenge trial has recently been published by Killingley et al. We review its findings and explain why this particular juncture in time makes additional challenge trials for COVID-19 and for other diseases justified and important.
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spelling pubmed-91241572022-05-23 A new day for human challenge trials? Rohrig, Abie Eyal, Nir Trends Mol Med Spotlight Two years into the coronavirus disease 2019 (COVID-19) pandemic and following several hot debates, the world’s first COVID-19 human challenge trial has recently been published by Killingley et al. We review its findings and explain why this particular juncture in time makes additional challenge trials for COVID-19 and for other diseases justified and important. Elsevier Ltd. 2022-07 2022-05-22 /pmc/articles/PMC9124157/ /pubmed/35610124 http://dx.doi.org/10.1016/j.molmed.2022.05.002 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Spotlight
Rohrig, Abie
Eyal, Nir
A new day for human challenge trials?
title A new day for human challenge trials?
title_full A new day for human challenge trials?
title_fullStr A new day for human challenge trials?
title_full_unstemmed A new day for human challenge trials?
title_short A new day for human challenge trials?
title_sort new day for human challenge trials?
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124157/
https://www.ncbi.nlm.nih.gov/pubmed/35610124
http://dx.doi.org/10.1016/j.molmed.2022.05.002
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