m(6)Am methyltransferase PCIF1 is essential for aggressiveness of gastric cancer cells by inhibiting TM9SF1 mRNA translation

PCIF1 (phosphorylated CTD interacting factor 1) is the first reported RNA N6,2′-O-dimethyladenosine (m(6)Am) methyltransferase. However, the pathological significance of PCIF1 and m(6)Am modification remains unknown. Here we find that both PCIF1 expression and m(6)Am modification are significantly e...

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Detalles Bibliográficos
Autores principales: Zhuo, Wei, Sun, Meng, Wang, Kun, Zhang, Lu, Li, Kai, Yi, Danyang, Li, Mengjie, Sun, Qiang, Ma, Xixi, Liu, Wei, Teng, Lisong, Yi, Chengqi, Zhou, Tianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124189/
https://www.ncbi.nlm.nih.gov/pubmed/35597784
http://dx.doi.org/10.1038/s41421-022-00395-1

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