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PHF13 epigenetically activates TGFβ driven epithelial to mesenchymal transition

Epigenetic alteration is a pivotal factor in tumor metastasis. PHD finger protein 13 (PHF13) is a recently identified epigenetic reader of H3K4me2/3 that functions as a transcriptional co-regulator. In this study, we demonstrate that PHF13 is required for pancreatic-cancer-cell growth and metastasis...

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Detalles Bibliográficos
Autores principales:	Sun, Yating, Li, Dan, Liu, Hongmei, Huang, Yongye, Meng, Fanyu, Tang, Jiahao, Li, Zhanjun, Xie, Wanhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124206/ https://www.ncbi.nlm.nih.gov/pubmed/35597793 http://dx.doi.org/10.1038/s41419-022-04940-4

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